50岁熟妇的呻吟声对白,精品播放久久久久久,粗大老头让我欲仙欲死,欧美黑人又粗又大的性格特点

歡迎來到凱學(xué)生物科技(上海)有限公司網(wǎng)站!

熱門關(guān)鍵詞:進(jìn)口ELISA試劑盒,人ELISA試劑盒,大鼠elisa試劑盒價(jià)格,小鼠elisa試劑盒價(jià)格,豬elisa試劑盒,雞elisa試劑盒,兔elisa試劑盒,魚elsa試劑盒,其他種屬elisa試劑盒,豚鼠elisa試劑盒,倉鼠elisa試劑盒,裸鼠ELISA試劑盒,進(jìn)口試劑,血清,動(dòng)物血清,人血清,胎牛血清,氨基酸試劑,培養(yǎng)基,顯色培養(yǎng)基,大腸桿菌O157培養(yǎng)基,細(xì)菌總數(shù)培養(yǎng)基,金黃色葡萄球菌檢驗(yàn)培養(yǎng)基,沙門氏菌/賀氏菌檢驗(yàn)培養(yǎng)基, 弧菌檢驗(yàn)培養(yǎng)基,其他培養(yǎng)基,酵母 霉菌 青霉 曲霉培養(yǎng)基, 李斯特氏菌檢驗(yàn)培養(yǎng)基,抗體,二抗,一抗,生物試劑,酶生物試劑,蛋白質(zhì)試劑,抗生素試劑,植物激素及核酸試劑,碳水化合物試劑,色素試劑,維生素試劑,表面活性劑,緩沖試劑,其他生化試劑,標(biāo)準(zhǔn)品對(duì)照品類,對(duì)照品,對(duì)照藥材,標(biāo)準(zhǔn)品,標(biāo)準(zhǔn)試劑,Spectrum試劑,美國藥典級(jí)試劑等

技術(shù)文章您現(xiàn)在的位置:首頁 > 技術(shù)文章 > DFX是游離鐵螯合劑

DFX是游離鐵螯合劑

更新時(shí)間:2017-08-25   點(diǎn)擊次數(shù):4772次

 DFX是游離鐵螯合劑 

Abstract

Signaling by transforming growth factor (TGF)-beta family members is mediated by Smad proteins that regulate gene transcription through functional cooperativity and association with other DNA-binding proteins. The hypoxia-inducible factor (HIF)-1 is a transcriptional complex that plays a key role in oxygen-regulated gene expression. We demonstrate that hypoxia and TGF-beta cooperate in the induction of the promoter activity of vascular endothelial growth factor (VEGF), which is a major stimulus in the promotion of angiogenesis. This cooperation has been mapped on the human VEGF promoter within a region at -1006 to -954 that contains functional DNA-binding sequences for HIF-1 and Smads. Optimal HIF-1alpha-dependent induction of the VEGF promoter was obtained in the presence of Smad3, suggesting an interaction between these proteins. Consistent with this, co-immunoprecipitation experiments revealed that HIF-1alpha physically associates with Smad3. These results demonstrate that both TGF-beta and hypoxia signaling pathways can synergize in the regulation of VEGF gene expression at the transcriptional level.

景德镇市| 安陆市| 理塘县| 余庆县| 云南省| 阳东县| 甘德县| 五莲县| 呈贡县| 乌兰察布市| 建瓯市| 阳新县| 荃湾区| 花莲县| 洪泽县| 安泽县| 康平县| 册亨县| 周口市| 黄石市| 屏东县| 墨玉县| 平昌县| 班玛县| 金坛市| 民权县| 库伦旗| 广水市| 龙岩市| 抚州市| 公安县| 鹰潭市| 安丘市| 剑川县| 拜泉县| 营山县| 高雄县| 金平| 黎平县| 会宁县| 庄浪县|